Extent of late gadolinium enhancement in patients with hypertrophic cardiomyopathy in correlation with serum MMP9 as an indicator of myocardial fibrosis
نویسندگان
چکیده
Results Nine out of 50 patients with HCM (18 %) showed no fibrosis on LGE-CMR. In the remaining 41 patients, mean size of fibrosis was 13,3 ± 10,3% on LGE-CMR. In all patients, the mean MMP9 level was 54,4 ± 35,2 ng/ ml. Size of fibrosis on LGE-CMR strongly correlated with MMP9 levels (R2 = 0,557, Pearson’s r = 0,75, p < 0,01). In the 9 patients with no LGE, MMP9 was with 29,6 ± 14,2 ng/ml significantly lower compared to the 41 patients with LGE and levels of 59,8 ± 36,2 ng/ml (p = 0,01).
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